Table 2

Allelic and genotypic frequency comparison between fetal and control groups.

C677T-MTHFR

Genotype-Allele

Frequencies by date of birth

82–84

85–87

88–90


Fetal Group

(n = 110)

(n = 129)

(n = 105)


%

n

%

n

%

n


CC

0.073**

8

0.008**

1

0.019**

2

CT

0.727**

80

0.705**

91

0.6*#

63

TT

0.2

22

0.287

37

0.381##

40

C allele

0.436**

96

0.36**

93

0.319**#

67

T allele

0.564**

124

0.64**

165

0.681**#

143

Control Group

(n = 88)

(n = 93)

(n = 95)


%

n

%

n

%

n


CC

0.33

29

0.301

28

0.305

29

CT

0.477

42

0.452

42

0.421

40

TT

0.193

17

0.247

23

0.274

26

C allele

0.568

100

0.527

98

0.516

98

T allele

0.432

76

0.473

88

0.484

92


Note: *p < 0.05; **p < 0.01 (significant values relative to controls). #p < 0.05; ##p < 0.01 (significant values relative to the 1982–1984 period)

Mayor-Olea et al. BMC Medical Genetics 2008 9:104   doi:10.1186/1471-2350-9-104

Open Data