References

  1. Clevenger CV, Furth PA, Hankinson SE, Schuler LA: The role of prolactin in mammary carcinoma.

    Endocr Rev 2003, 24:1-27. PubMed Abstract | Publisher Full Text | PubMed Central Full Text OpenURL

  2. Yen SS, Jaffe RB: Reproductive endocrinology. 4th edition edition. Philadelphia, PA, Saunders; 1999:257-283. OpenURL

  3. Muhlbock O, Boot LM: Induction of mammary cancer in mice without the mammary tumor agent by isografts of hypophyses.

    Cancer Res 1959, 19:402-412. PubMed Abstract OpenURL

  4. Boot LM, Muhlbock O, Ropcke G: Prolactin and the induction of mammary tumors in mice.

    General and Comparative Endocrinology 1962, 2:601-602. OpenURL

  5. Welsch CW, Gribler C: Prophylaxis of spontaneously developing mammary carcinoma in C3H-HeJ female mice by suppression of prolactin.

    Cancer Res 1973, 33:2939-2946. PubMed Abstract | Publisher Full Text OpenURL

  6. Welsch CW, Nagasawa H: Prolactin and murine mammary tumorigenesis: a review.

    Cancer Res 1977, 37:951-963. PubMed Abstract | Publisher Full Text OpenURL

  7. Liby K, Neltner B, Mohamet L, Menchen L, Ben-Jonathan N: Prolactin overexpression by MDA-MB-435 human breast cancer cells accelerates tumor growth.

    Breast Cancer Res Treat 2003, 79:241-252. PubMed Abstract | Publisher Full Text OpenURL

  8. Schroeder MD, Symowicz J, Schuler LA: PRL modulates cell cycle regulators in mammary tumor epithelial cells.

    Mol Endocrinol 2002, 16:45-57. PubMed Abstract | Publisher Full Text OpenURL

  9. Gutzman JH, Miller KK, Schuler LA: Endogenous human prolactin and not exogenous human prolactin induces estrogen receptor alpha and prolactin receptor expression and increases estrogen responsiveness in breast cancer cells.

    J Steroid Biochem Mol Biol 2004, 88:69-77. PubMed Abstract | Publisher Full Text OpenURL

  10. Ormandy CJ, Hall RE, Manning DL, Robertson JF, Blamey RW, Kelly PA, Nicholson RI, Sutherland RL: Coexpression and cross-regulation of the prolactin receptor and sex steroid hormone receptors in breast cancer.

    J Clin Endocrinol Metab 1997, 82:3692-3699. PubMed Abstract | Publisher Full Text OpenURL

  11. Maus MV, Reilly SC, Clevenger CV: Prolactin as a chemoattractant for human breast carcinoma.

    Endocrinology 1999, 140:5447-5450. PubMed Abstract | Publisher Full Text OpenURL

  12. Struman I, Bentzien F, Lee H, Mainfroid V, D'Angelo G, Goffin V, Weiner RI, Martial JA: Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis.

    Proc Natl Acad Sci U S A 1999, 96:1246-1251. PubMed Abstract | Publisher Full Text | PubMed Central Full Text OpenURL

  13. Touraine P, Martini JF, Zafrani B, Durand JC, Labaille F, Malet C, Nicolas A, Trivin C, Postel-Vinay MC, Kuttenn F, Kelly PA: Increased expression of prolactin receptor gene assessed by quantitative polymerase chain reaction in human breast tumors versus normal breast tissues.

    J Clin Endocrinol Metab 1998, 83:667-674. PubMed Abstract | Publisher Full Text OpenURL

  14. Ben-Jonathan N, Liby K, McFarland M, Zinger M: Prolactin as an autocrine/paracrine growth factor in human cancer.

    Trends Endocrinol Metab 2002, 13:245-250. PubMed Abstract | Publisher Full Text OpenURL

  15. Clevenger CV, Chang WP, Ngo W, Pasha TL, Montone KT, Tomaszewski JE: Expression of prolactin and prolactin receptor in human breast carcinoma. Evidence for an autocrine/paracrine loop.

    Am J Pathol 1995, 146:695-705. PubMed Abstract | PubMed Central Full Text OpenURL

  16. Tworoger SS, Eliassen AH, Rosner B, Sluss P, Hankinson SE: Plasma prolactin concentrations and risk of postmenopausal breast cancer.

    Cancer Res 2004, 64:6814-6819. PubMed Abstract | Publisher Full Text OpenURL

  17. Manjer J, Johansson R, Berglund G, Janzon L, Kaaks R, Agren A, Lenner P: Postmenopausal breast cancer risk in relation to sex steroid hormones, prolactin, and SHBG (Sweden).

    Cancer Causes Control 2003, 14:599-607. PubMed Abstract | Publisher Full Text OpenURL

  18. Wang DY, De Stavola BL, Bulbrook RD, Allen DS, Kwa HG, Fentiman IS, Hayward JL, Millis RR: Relationship of blood prolactin levels and the risk of subsequent breast cancer.

    Int J Epidemiol 1992, 21:214-221. PubMed Abstract | Publisher Full Text OpenURL

  19. Kabuto M, Akiba S, Stevens RG, Neriishi K, Land CE: A prospective study of estradiol and breast cancer in Japanese women.

    Cancer Epidemiol Biomarkers Prev 2000, 9:575-579. PubMed Abstract | Publisher Full Text OpenURL

  20. Cole EN, England PC, Sellwood RA, Griffiths K: Serum prolactin concentrations throughout the menstrual cycle of normal women and patients with recent breast cancer.

    Eur J Cancer 1977, 13:677-684. PubMed Abstract OpenURL

  21. Malarkey WB, Schroeder LL, Stevens VC, James AG, Lanese RR: Disordered nocturnal prolactin regulation in women with breast cancer.

    Cancer Res 1977, 37:4650-4654. PubMed Abstract | Publisher Full Text OpenURL

  22. Rose DP, Pruitt BT: Plasma prolactin levels in patients with breast cancer.

    Cancer 1981, 48:2687-2691. PubMed Abstract | Publisher Full Text OpenURL

  23. Meyer F, Brisson J, Morrison AS, Brown JB: Endogenous sex hormones, prolactin, and mammographic features of breast tissue in premenopausal women.

    J Natl Cancer Inst 1986, 77:617-620. PubMed Abstract OpenURL

  24. Love RR, Rose DR, Surawicz TS, Newcomb PA: Prolactin and growth hormone levels in premenopausal women with breast cancer and healthy women with a strong family history of breast cancer.

    Cancer 1991, 68:1401-1405. PubMed Abstract | Publisher Full Text OpenURL

  25. Ingram DM, Nottage EM, Roberts AN: Prolactin and breast cancer risk.

    Med J Aust 1990, 153:469-473. PubMed Abstract OpenURL

  26. Secreto G, Recchione C, Cavalleri A, Miraglia M, Dati V: Circulating levels of testosterone, 17 beta-oestradiol, luteinising hormone and prolactin in postmenopausal breast cancer patients.

    Br J Cancer 1983, 47:269-275. PubMed Abstract OpenURL

  27. Bernstein L, Ross RK: Endogenous hormones and breast cancer risk.

    Epidemiol Rev 1993, 15:48-65. PubMed Abstract | Publisher Full Text OpenURL

  28. Helzlsouer KJ, Alberg AJ, Bush TL, Longcope C, Gordon GB, Comstock GW: A prospective study of endogenous hormones and breast cancer.

    Cancer Detect Prev 1994, 18:79-85. PubMed Abstract OpenURL

  29. Tworoger SS, Eliassen AH, Sluss P, Hankinson SE: A prospective study of plasma prolactin concentrations and risk of premenopausal and postmenopausal breast cancer.

    J Clin Oncol 2007, 25:1482-1488. PubMed Abstract | Publisher Full Text OpenURL

  30. Truong AT, Duez C, Belayew A, Renard A, Pictet R, Bell GI, Martial JA: Isolation and characterization of the human prolactin gene.

    Embo J 1984, 3:429-437. PubMed Abstract | PubMed Central Full Text OpenURL

  31. Berwaer M, Martial JA, Davis JR: Characterization of an up-stream promoter directing extrapituitary expression of the human prolactin gene.

    Mol Endocrinol 1994, 8:635-642. PubMed Abstract | Publisher Full Text OpenURL

  32. DiMattia GE, Gellersen B, Duckworth ML, Friesen HG: Human prolactin gene expression. The use of an alternative noncoding exon in decidua and the IM-9-P3 lymphoblast cell line.

    J Biol Chem 1990, 265:16412-16421. PubMed Abstract | Publisher Full Text OpenURL

  33. Arden KC, Boutin JM, Djiane J, Kelly PA, Cavenee WK: The receptors for prolactin and growth hormone are localized in the same region of human chromosome 5.

    Cytogenet Cell Genet 1990, 53:161-165. PubMed Abstract OpenURL

  34. Hu ZZ, Zhuang L, Meng J, Tsai-Morris CH, Dufau ML: Complex 5' genomic structure of the human prolactin receptor: multiple alternative exons 1 and promoter utilization.

    Endocrinology 2002, 143:2139-2142. PubMed Abstract | Publisher Full Text OpenURL

  35. Hu ZZ, Zhuang L, Meng J, Leondires M, Dufau ML: The human prolactin receptor gene structure and alternative promoter utilization: the generic promoter hPIII and a novel human promoter hP(N).

    J Clin Endocrinol Metab 1999, 84:1153-1156. PubMed Abstract | Publisher Full Text OpenURL

  36. Hu ZZ, Meng J, Dufau ML: Isolation and characterization of two novel forms of the human prolactin receptor generated by alternative splicing of a newly identified exon 11.

    J Biol Chem 2001, 276:41086-41094. PubMed Abstract | Publisher Full Text OpenURL

  37. Trott JF, Hovey RC, Koduri S, Vonderhaar BK: Alternative splicing to exon 11 of human prolactin receptor gene results in multiple isoforms including a secreted prolactin-binding protein.

    J Mol Endocrinol 2003, 30:31-47. PubMed Abstract | Publisher Full Text OpenURL

  38. Dunning AM, Dowsett M, Healey CS, Tee L, Luben RN, Folkerd E, Novik KL, Kelemen L, Ogata S, Pharoah PD, Easton DF, Day NE, Ponder BA: Polymorphisms associated with circulating sex hormone levels in postmenopausal women.

    J Natl Cancer Inst 2004, 96:936-945. PubMed Abstract | Publisher Full Text OpenURL

  39. Miller DT, Zee RY, Suk Danik J, Kozlowski P, Chasman DI, Lazarus R, Cook NR, Ridker PM, Kwiatkowski DJ: Association of common CRP gene variants with CRP levels and cardiovascular events.

    Ann Hum Genet 2005, 69:623-638. PubMed Abstract | Publisher Full Text OpenURL

  40. de Bakker PI, Yelensky R, Pe'er I, Gabriel SB, Daly MJ, Altshuler D: Efficiency and power in genetic association studies.

    Nat Genet 2005, 37:1217-1223. PubMed Abstract | Publisher Full Text OpenURL

  41. Canbay E, Degerli N, Gulluoglu BM, Kaya H, Sen M, Bardakci F: Could prolactin receptor gene polymorphism play a role in pathogenesis of breast carcinoma?

    Curr Med Res Opin 2004, 20:533-540. PubMed Abstract | Publisher Full Text OpenURL

  42. Haiman CA, Stram DO, Pike MC, Kolonel LC, Burtt NP, Altshuler D, Hirschhorn J, Henderson BE: A comprehensive haplotype analysis of CYP19 and breast cancer risk: the Multiethnic Cohort.

    Hum Mol Genet 2003, 12:2679-2692. PubMed Abstract | Publisher Full Text OpenURL

  43. Gabriel SB, Schaffner SF, Nguyen H, Moore JM, Roy J, Blumenstiel B, Higgins J, DeFelice M, Lochner A, Faggart M, Liu-Cordero SN, Rotimi C, Adeyemo A, Cooper R, Ward R, Lander ES, Daly MJ, Altshuler D: The structure of haplotype blocks in the human genome.

    Science 2002, 296:2225-2229. PubMed Abstract | Publisher Full Text OpenURL

  44. Stram DO, Haiman CA, Hirschhorn JN, Altshuler D, Kolonel LN, Henderson BE, Pike MC: Choosing haplotype-tagging SNPS based on unphased genotype data using a preliminary sample of unrelated subjects with an example from the Multiethnic Cohort Study.

    Hum Hered 2003, 55(1):227-236. Publisher Full Text OpenURL

  45. Stevens A, Ray D, Alansari A, Hajeer A, Thomson W, Donn R, Ollier WE, Worthington J, Davis JR: Characterization of a prolactin gene polymorphism and its associations with systemic lupus erythematosus.

    Arthritis & Rheumatism 2001, 44:2358-2366. Publisher Full Text OpenURL

  46. Stevens A, Ray DW, Worthington J, Davis JR: Polymorphisms of the human prolactin gene--implications for production of lymphocyte prolactin and systemic lupus erythematosus.

    Lupus 2001, 10:676-683. PubMed Abstract | Publisher Full Text OpenURL

  47. Vaclavicek A, Hemminki K, Bartram CR, Wagner K, Wappenschmidt B, Meindl A, Schmutzler RK, Klaes R, Untch M, Burwinkel B, Forsti A: Association of prolactin and its receptor gene regions with familial breast cancer.

    Journal of Clinical Endocrinology & Metabolism 2006, 91:1513-1519. Publisher Full Text OpenURL

  48. International HapMap Project [http://www.hapmap.org]

    OpenURL

  49. Kolonel LC, Henderson BE, Hankin JH, Nomura AMY, Wilkens LR, Pike MC, Stram DO, Monroe KR, Earle ME, Nagamine FS: A multiethnic cohort in Hawaii and Los Angeles: Baseline Characteristics.

    American Journal of Epidemiology 2000, 151:346-357. PubMed Abstract | Publisher Full Text OpenURL

  50. National Center of Biotechnology Information [http://www.ncbi.nlm.nih.gov/projects/SNP]

    OpenURL

  51. Celera [http://www.celera.com]

    OpenURL

  52. Excoffier L, Slatkin M: Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population.

    Mol Biol Evol 1995, 12:921-927. PubMed Abstract | Publisher Full Text OpenURL

  53. TagSNPs Program [http://www-rcf.usc.edu/~stram]

    OpenURL

  54. Stram DO: Tag SNP selection for association studies.

    Genet Epidemiol 2004, 27:365-374. PubMed Abstract | Publisher Full Text OpenURL

  55. Hankinson SE, London SJ, Chute CG, Barbieri RL, Jones L, Kaplan LA, Sacks FM, Stampfer MJ: Effect of transport conditions on the stability of biochemical markers in blood.

    Clin Chem 1989, 35:2313-2316. PubMed Abstract | Publisher Full Text OpenURL

  56. Freedman ML, Penney KL, Stram DO, Le Marchand L, Hirschhorn JN, Kolonel LN, Altshuler D, Henderson BE, Haiman CA: Common variation in BRCA2 and breast cancer risk: a haplotype-based analysis in the Multiethnic Cohort.

    Human Molecular Genetics 2004, 13:2431-2441. PubMed Abstract | Publisher Full Text OpenURL

  57. International HapMap C: A haplotype map of the human genome.[see comment].

    Nature 2005, 437:1299-1320. PubMed Abstract | Publisher Full Text | PubMed Central Full Text OpenURL

  58. Rosenberg NA, Pritchard JK, Weber JL, Cann HM, Kidd KK, Zhivotovsky LA, Feldman MW: Genetic structure of human populations.[see comment].

    Science 2002, 298:2381-2385. PubMed Abstract | Publisher Full Text OpenURL

  59. Ioannidis JP, Ntzani EE, Trikalinos TA: 'Racial' differences in genetic effects for complex diseases.[see comment].

    Nature Genetics 2004, 36:1312-1318. PubMed Abstract | Publisher Full Text OpenURL

  60. Zaykin DV, Westfall PH, Young SS, Karnoub MA, Wagner MJ, Ehm MG: Testing association of statistically inferred haplotypes with discrete and continuous traits in samples of unrelated individuals.

    Hum Hered 2002, 53:79-91. PubMed Abstract | Publisher Full Text OpenURL

  61. LocusView [http://www.broad.mit.edu/mpg/locusview/]

    OpenURL