Table 2 |
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|
Lymphocyte subpopulations in members of family 86 |
||||||
|
Percent of lymphoid cells (absolute numbers/mm3) |
||||||
|
|
||||||
|
Pt |
Sib1 |
Sib2 |
Mother |
Father |
Controls** |
|
|
|
||||||
|
Total T Cells |
||||||
|
CD3 |
64.7(2750) |
78.6(1336) |
80.3(1767) |
71.1(1138) |
65.1(1172) |
(832–2028) |
|
CD5 |
62.8(2669) |
79.3(1348) |
81.8(1800) |
72.4(1158) |
68.8(1238) |
(828–1994) |
|
CD3/ab |
51.8(2202) |
47.1(801) |
75.4(1659) |
69.9(1118) |
64(1152) |
(620–2010) |
|
CD3/gd |
12(510) |
5.3(90) |
5.3(117) |
0.9(14) |
0.9 (16) |
(9–166) |
|
T Cell Subsets |
||||||
|
CD4 |
36.1(1534) |
43.3(736) |
52(1144) |
41.9(670) |
40.6(731) |
(480–1339) |
|
CD8 |
26.7(1135) |
31.8(541) |
31.6(695) |
33.5(536) |
29.6(533) |
(351–911) |
|
CD3+CD4-CD8- |
9.7(412) |
4.6(78) |
4.9(108) |
1.1(18) |
1.3(23) |
(9–122) |
|
DNT/ab* |
1.1(47) |
0.8(14) |
1.1(24) |
0.5(8) |
0.5(9) |
(2–18) |
|
DNT/gd |
7.9(336) |
3.9(66) |
3.4(75) |
0.6(10) |
0.7(13) |
(5–59) |
|
T Cell Activation |
||||||
|
CD4+/HLA-DR+ |
14.2(604) |
1.6(27) |
2.3(51) |
2.8(45) |
2.7(49) |
(< = 95) |
|
CD4+/CD25+ |
5.2(221) |
16.1(274) |
11(242) |
19.7(315) |
22.1(398) |
|
|
Total B cells |
||||||
|
CD20 |
18.9(803) |
8.8(150) |
8.1(178) |
5.9(94) |
19.6(353) |
(88–330) |
|
|
||||||
|
*DNT: Double-negative CD4- CD8- T cells, either TCRαβ+ or TCRγδ+ ** 95% confidence intervals for adult normals. |
||||||
|
Bi et al. BMC Medical Genetics 2007 8:41 doi:10.1186/1471-2350-8-41 |
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