Table 2

Lymphocyte subpopulations in members of family 86

Percent of lymphoid cells (absolute numbers/mm3)


Pt

Sib1

Sib2

Mother

Father

Controls**


    Total T Cells

CD3

64.7(2750)

78.6(1336)

80.3(1767)

71.1(1138)

65.1(1172)

(832–2028)

CD5

62.8(2669)

79.3(1348)

81.8(1800)

72.4(1158)

68.8(1238)

(828–1994)

CD3/ab

51.8(2202)

47.1(801)

75.4(1659)

69.9(1118)

64(1152)

(620–2010)

CD3/gd

12(510)

5.3(90)

5.3(117)

0.9(14)

0.9 (16)

(9–166)

    T Cell Subsets

CD4

36.1(1534)

43.3(736)

52(1144)

41.9(670)

40.6(731)

(480–1339)

CD8

26.7(1135)

31.8(541)

31.6(695)

33.5(536)

29.6(533)

(351–911)

CD3+CD4-CD8-

9.7(412)

4.6(78)

4.9(108)

1.1(18)

1.3(23)

(9–122)

DNT/ab*

1.1(47)

0.8(14)

1.1(24)

0.5(8)

0.5(9)

(2–18)

DNT/gd

7.9(336)

3.9(66)

3.4(75)

0.6(10)

0.7(13)

(5–59)

    T Cell Activation

CD4+/HLA-DR+

14.2(604)

1.6(27)

2.3(51)

2.8(45)

2.7(49)

(< = 95)

CD4+/CD25+

5.2(221)

16.1(274)

11(242)

19.7(315)

22.1(398)

    Total B cells

CD20

18.9(803)

8.8(150)

8.1(178)

5.9(94)

19.6(353)

(88–330)


*DNT: Double-negative CD4- CD8- T cells, either TCRαβ+ or TCRγδ+

** 95% confidence intervals for adult normals.

Bi et al. BMC Medical Genetics 2007 8:41   doi:10.1186/1471-2350-8-41

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