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Open AccessResearch article

The genetic study of three population microisolates in South Tyrol (MICROS): study design and epidemiological perspectives

Cristian Pattaro1 email, Fabio Marroni1 email, Alice Riegler1 email, Deborah Mascalzoni1 email, Irene Pichler1 email, Claudia B Volpato1 email, Umberta Dal Cero1 email, Alessandro De Grandi1 email, Clemens Egger1 email, Agatha Eisendle1 email, Christian Fuchsberger1 email, Martin Gögele1 email, Sara Pedrotti1 email, Gerd K Pinggera1 email, Stefan A Stefanov1 email, Florian D Vogl2 email, Christian J Wiedermann3,4 email, Thomas Meitinger5,6 email and Peter P Pramstaller1,7,8 email

Institute of Genetic Medicine, European Academy, Bolzano, Italy

Department of Gynaecology, Hospital of Merano, Via Rossini 5, 39012 Merano-Meran, Italy

Laboratory of Medical Intensive Care, Division of General Internal Medicine, Department of Medicine, Medical University of Innsbruck, Innsbruck, Austria

Division of Internal Medicine II, Department of Medicine, Central Hospital of Bolzano, Bolzano/Bozen, Italy

Institute of Human Genetics, Technical University of Munich, Munich, Germany

GSF – National Research Center for Environment and Health, Institute of Human Genetics, München-Neuherberg, Germany

Department of Neurology, University of Lübeck, Lübeck, Germany

Department of Neurology, General Regional Hospital, Bolzano, Italy

author email corresponding author email

BMC Medical Genetics 2007, 8:29doi:10.1186/1471-2350-8-29

Published: 5 June 2007

Additional files

Additional file 1:

Distribution of cardiovascular and respiratory traits. Prevalence of the main cardiovascular disease symptoms (upper panel) and respiratory traits (lower panel), by age and sex (solid line = females, dashed line = males), with 95% confidence intervals.

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Additional file 2:

Distribution of cardiovascular disease's determinants. Differential distribution of six quantitative traits by age and sex (males: gray; females: white). Age is reported on the x-axis.

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Additional file 3:

Distribution of liver-related intermediate phenotypes. Distribution of glutamic-oxaloacetic transaminase (GOT), glutamate pyruvate transaminase (GPT) and gamma glutamyl-transpeptidase (GGT), by age and sex (gray = males, white = females).

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