Table 1 |
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Clinical and laboratory features of 47 patients suffering from PCOS and 45 controls included in this genetic study |
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|
Characteristics |
PCOS (n = 47) |
Normal (n = 45) |
P |
|
|
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|
Age (years) |
26.3 ± 5.4 |
24.6 ± 3.9 |
NS |
|
Acanthosis nigrans (%) |
31.9% |
0% |
<0.05 |
|
Body weight (kg) |
72.4 ± 14.5 |
56.4 ± 9.8 |
<0.05 |
|
BMI (kg/m2) |
28.5 ± 6.0 |
21.7 ± 3.2 |
<0.05 |
|
LH/FSH |
2.1 ± 1.0 |
1.3 ± 0.6 |
<0.05 |
|
Prolactin (ng/ml) |
18.6 ± 8.0 |
12.7 ± 6.3 |
NS |
|
Testosterone (ng/ml) |
1.3 ± 0.5 |
0.5 ± 0.2 |
<0.05 |
|
SHBG |
21.1 ± 8.3 |
48.1 ± 7.8 |
<0.05 |
|
Fasting glucose (mg/dl) |
91.3 ± 18.1 |
86.3 ± 17.6 |
NS |
|
IGT (%) |
36.2% |
6.25% |
<0.05 |
|
AGT (%) |
46.8% |
6.25% |
<0.05 |
|
Fasting insulin (uU/ml) |
24.4 ± 17.2 |
7.9 ± 6.7 |
<0.05 |
|
Glucose/insulin ratio |
5.27 ± 3.34 |
12.13 ± 4.94 |
<0.05 |
|
HOMAIR |
5.21 ± 3.73 |
1.59 ± 0.65 |
<0.05 |
|
|
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PCOS = polycystic ovary syndrome; BMI = body mass index; SHBG = sex hormone binding globulin; IGT = intolerance of 75 gm oral glucose tolerance test; Glucose/insulin ratio = fasting glucose (mg/dl)/fasting insulin (uU/ml); AGT = abnormal glucose tolerance; HOMAIR(Homeostasis model assessment index for insulin resistance) = fasting insulin (uU/ml) × fasting glucose (mg/dl)/405 |
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Lin et al. BMC Medical Genetics 2006 7:36 doi:10.1186/1471-2350-7-36 |
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