|
Genotype and allele frequencies of the Pro104Leu and 3'UTR 1239C>A polymorphisms according to obesity status by gender. |
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| Men |
Women |
|||||||
|
|
|
|||||||
| Normal weight |
Overweight |
Obese |
p* |
Normal weight |
Overweight |
Obese |
p* |
|
|
|
|
|||||||
| Pro104Pro, n (%) |
140 (60.9) |
147 (60.8) |
61 (59.2) |
153 (59.5) |
103 (59.2) |
83 (65.4) |
||
| Pro104Leu, n (%) |
83 (36.1) |
78 (32.2) |
37 (35.9) |
0.36 |
90 (35.0) |
60 (34.5) |
40 (31.5) |
0.67 |
| Leu104Leu, n (%) |
7 (3.0) |
17 (7.0) |
5 (4.9) |
14 (5.5) |
11 (6.3) |
4 (3.1) |
||
| Total |
230 |
242 |
103 |
257 |
174 |
127 |
||
|
|
|
|||||||
| 1239CC, n (%) |
162 (69.5) |
158 (66.1) |
67 (65.1) |
176 (68.8) |
119 (68.4) |
84 (65.6) |
||
| 1239CA, n (%) |
62 (26.6) |
72 (30.1) |
34 (33.0) |
0.69 |
74 (28.9) |
53 (30.5) |
40 (31.3) |
0.78 |
| 1239AA, n (%) |
9 (3.9) |
9 (3.8) |
2 (1.9) |
6 (2.3) |
2 (1.1) |
4 (3.1) |
||
| Total |
233 |
239 |
103 |
256 |
174 |
128 |
||
|
* p values for the 3*3 analysis. Normal weight: BMI < 25 kg/m2, overweight: 25 ≤ BMI < 30 kg/m2, obese: BMI ≥ 30 kg/m2. | ||||||||
Meirhaeghe et al. BMC Medical Genetics 2006 7:26 doi:10.1186/1471-2350-7-26 |
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