Table 1

General characterization of C282Y homozygous probands at the time of diagnosis according to gender


Males n = 32
Females n = 11
p*

Age (years)
51 ± 13 (29–75)
47 ± 11 (32–65)
n.s.
Transferrin Saturation (%)
92 (87–97)
83 (75–92)
n.s.
Ferritin (ng/ml)
2694 (2006–3383)
1353 (122–2584)
n.s.
Total Body Iron Stores (g)
9.86 (8.19–11.54)
6.11 (3.21–9.02)
0.030

Total lymphocytes (×106/ml)
1.91 (1.69–2.13)
2.30 (1.92–2.67)
n.s.
Total CD4+ cells(×106/ml)
0.98 (0.84–1.11)
1.09 (0.85–1.32)
n.s.
Total CD8+ cells(×106/ml)
0.35 (0.28–0.42)
0.48 (0.36–0.59)
n.s.

Parameters are expressed as mean (95% confidence intervals) except age, which is expressed as mean ± standard deviation (maximum – minimum values).

Estimation of TBIS was obtained in 27 males and 9 females.

*Statistically significant differences between groups (p) were tested using Student's T test.

Cruz et al. BMC Medical Genetics 2006 7:16   doi:10.1186/1471-2350-7-16