Table 6 |
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|
Summary of haplotype scores representing associations between blood pressure and haplotypes in the AIB phase II population showing overall statistical significance values |
||||||
|
Haplotypes (amino acid) |
EVEa |
KVGa |
KVEa |
EMEa |
Overall p-val |
|
|
|
||||||
|
Daytime DBP |
Haplotype scoreb |
-0.136 |
-0.266 |
0.890 |
-0.726 |
0.76 |
|
Haplotype scoreb (adjusted*) |
-0.361 |
-0.192 |
0.985 |
-0.565 |
0.77 |
|
|
Nighttime SBP |
Haplotype scoreb |
-0.657 |
1.676 |
-0.576 |
-0.586 |
0.40 |
|
Haplotype scoreb (adjusted*) |
-0.803 |
1.676 |
-0.573 |
-0.294 |
0.42 |
|
|
Nighttime DBP |
Haplotype scoreb |
-1.313 |
1.313 |
0.665 |
-0.699 |
0.41 |
|
Haplotype scoreb (adjusted*) |
-1.453 |
1.177 |
0.706 |
-0.260 |
0.47 |
|
|
|
||||||
|
* Adjusted for age, sex and alcohol intake a haplotypes defined from positions 128, 257 and 308 respectively b from the haplo.score method |
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|
Dolan et al. BMC Medical Genetics 2005 6:41 doi:10.1186/1471-2350-6-41 |
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