Table 4

Haplotype frequency estimation and test statistics between case and control.

Haplotypea

Patient

Normal

Fisher's Exact Test (P value)b

ORb,c,d

95% CId


TAGTAAGACA

0.340

0.359

0.755

0.919

0.61–1.38

TAGAGACCTG

0.145

0.140

1.000

1.035

0.59–1.80

GGTTGCCCTA

0.095

0.068

0.366

1.439

0.70–2.96

TAGTAACACA

0.010

0.039

0.105

0.250

0.05–1.19

TAGTAAGATA

0.025

0.010

0.278

2.615

0.50–13.64

TAGTGCGACA

0.025

0.015

0.498

1.735

0.41–7.36

GGGAGACCCA

0.025

0

0.028

--

--

TAGTAACCTG

0.020

0

0.058

--

--

TAGTGACCTG

0.020

0.010

0.443

2.081

0.38–11.49

TAGAGACATG

0.020

0.019

1.000

1.031

0.25–4.18

GGTTGCCCTG

0.020

0.010

0.443

2.082

0.38–11.49

GGTAGACCCA

0.015

0.024

0.724

0.612

0.14–2.59

Others

0.240

0.306

0.149

0.717

0.46–1.11

Total

0.082

P value of permutation test

0.602


a. The order of the markers, shown 5' → 3', is (left to right) T-1721G, A-1067G, G-347T, T3804A, G7465A, A12517C, C18626G, A20004C, C27224T, A27237G.

b. Chi-square, Fisher's Exact Test and Odds Ratio were calculated by using the SAS program.

c. The Odds Ratio could not be calculated for the haplotype GGGAGACCCA and TAGTAACCTG, because of the zero value in the population.

d. OR: odds Ratio; CI: confidence Interval.

Lai et al. BMC Medical Genetics 2005 6:14   doi:10.1186/1471-2350-6-14

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