Figure 3.

OSA using family-specific LOD scores as the ranking covariate. Families were ordered based on descending LOD scores at peak linkage for 19p13 and allele-sharing LOD scores calculated in the optimal subset for (A) chromosome 17 or (B) chromosome 6. Families were also ranked based on descending LOD scores at peak linkage on chromosome 7q (C), and LOD scores calculated for chromosome 5. Solid lines reflect multipoint LOD scores corresponding to the entire dataset for the chromosome being analyzed, while dashed lines represent analysis of the optimal subset (above the dataset division in all cases) identified from OSA; these were 52 families for chromosome 17, 30 for chromosome 6 and 41 families for chromosome 7.