Table 4

Effect of HLA-B* 4601 allele on severity of SARS patients

5 deceased or intubated probable SARS patients (Severe cases)

28 Excluded fever patients

Control A

101 high risk non-infected health care workers

HLA allele

Total number of alleles (n = 10)

Total number of alleles (n = 56)

OR

CI

P

Pc-value (20)^†

Total number of alleles (n = 202)

OR

CI

P

Pc-value (33)^†

B* 4601

6

9

7.83

1.83–33.47

0.007

n.s.

25

10.62

2.80–40.26

0.0008

0.0279

n= count of alleles; P = P-value; n.s. = not significant. ^† The correction factor (number of different alleles or number of comparisons) is shown within parenthesis; Pc-value = P × Correction factor (Edward, 1974).

Lin et al. BMC Medical Genetics 2003 4:9   doi:10.1186/1471-2350-4-9