Table 3

Complete meta-analysis results for African-Americans, effect size expressed in terms of % difference in mean BMI
Current smokers Former/never smokers Combined sex and smoking status*
Gene SNP CA sex p-value for interaction % difference in mean BMI (95% CI) p-value N % difference in mean BMI (95% CI) p-value N % difference in mean BMI (95% CI) p-value N AF
GNPDA2 rs10938397 G F 0.60 0.5 (-0.9 - 1.92) 0.50 1848 1.51 (0.6 - 2.43) 9.2E-04 7664 0.91 (0.3 - 1.41) 1.5E-03 14383 0.24
M 0.78 1.31 (-0.1 - 2.63) 0.06 1455 1.51 (0.4 - 2.53) 6.9E-03 2831
MC4R rs17782313 C F 0.53 −0.8 (-2.08 - 0.6) 0.27 1758 0.6 (-0.2 - 1.51) 0.15 7365 0.6 (0.03 - 1.11) 4.0E-02 13698 0.29
M 0.31 −0.1 (-1.29 - 1.21) 0.93 1339 1.21 (0.2 - 2.22) 0.02 2682
FTO rs3751812 T F 0.34 −0.1 (-2.76 - 2.63) 0.94 774 0.4 (-1.09 - 1.92) 0.61 4505 0.4 (-1.11 - 2.01) 0.60 4549 0.12
M 0.61 2.53 (0.2 - 4.92) 3.0E-02 329 1.51 (-0.3 - 3.25) 0.11 565
TMEM18 rs6548238 C F 0.10 0.1 (-1.78 - 2.02) 0.95 1876 1.82 (0.7 - 2.94) 0.002 7707 1.31 (0.6 - 2.01) 2.4E-04 14492 0.88
M 0.64 2.43 (0.7 - 4.08) 0.01 1463 0.9 (-0.4 - 2.22) 0.18 2855

CA Coded allele, M male, F female, CI confidence interval, AF coded allele frequency.

Fesinmeyer et al.

Fesinmeyer et al. BMC Medical Genetics 2013 14:6   doi:10.1186/1471-2350-14-6

Open Data