Table 3

Genotype distribution of the polymorphisms in the Czech population
Czech sample population
Gene SNP Allele Genotype distribution (D-DA-A) HWE Dominant modela
Name ID. (D/A) Controls (N) Cases (N) Controls OR (95% CI) p value
AGT rs699 T/C 225-354-181 244-492-226 0.07 1.26 (1.01-1.57) 0.04
GALNT2 rs4846914 A/G 291-348-114 372-450-142 0.55 1.03 (0.84-1.27) 0.76
GALNT2 rs611229 T/G 314-358-101 426-427-130 0.95 0.89 (0.73-1.09) 0.25
IFIH1 rs1990760 T/C 282-355-109 360-455-151 0.87 1.04 (0.85-1.28) 0.72
SLC2A2 rs5400 C/T 586-161-14 743-217-18 0.45 1.09 (0.86-1.38) 0.49
SLC2A2 rs6785233 T/G 643-120-6 828-146-8 0.88 0.99 (0.76-1.30) 0.95
SLC2A2 rs8192675 T/C 392-313-66 491-409-73 0.75 1.03 (0.85-1.26) 0.75
IGFBP2 rs1470579 A/C 389-290-82 494-376-104 0.01 1.01 (0.83-1.23) 0.91
ENPP1 rs1044498 A/C 573-184-19 773-200-13 0.36 0.79 (0.63-1.00) 0.05
ENPP1 rs9493119 A/G 720-54-1 916-69-5 0.99 1.17 (0.80-1.71) 0.42
CYP3A[x] rs10211 A/G 668-97-4 820-150-8 0.81 1.38 (1.04-1.83) 0.03
CYP3A[x] rs667660 A/C 668-93-4 830-144-8 0.70 1.24 (0.93-1.65) 0.14
MTMR9 rs10091637 T/C 174-394-194 229-496-257 0.34 0.97 (0.77-1.23) 0.79
MTMR9 rs11250127 A/G 105-376-290 150-431-388 0.33 0.87 (0.65-1.15) 0.32
ABCA1 rs4149268 G/A 309-363-94 398-458-119 0.42 1.02 (0.83-1.25) 0.87
GAD2 rs2236418 A/G 529-219-22 667-276-31 0.91 0.93 (0.75-1.15) 0.51
GAD2 rs2839670 C/A 526-217-22 672-277-35 0.95 0.94 (0.76-1.16) 0.57
GAD2 rs6482538 A/G 648-120-6 812-164-8 0.86 1.03 (0.80-1.35) 0.80
GAD2 rs7076544 A/G 520-230-20 645-304-34 0.36 1.02 (0.82-1.25) 0.88
GAD2 rs8190748 A/G 400-310-55 501-395-85 0.63 0.98 (0.80-1.19) 0.81
ERBB3 rs11171739 T/C 341-301-121 447-354-162 0.0001
KCTD10 rs7298565 G/A 158-349-248 185-449-344 0.09 1.19 (0.93-1.53) 0.16
CYP19A1 rs12592797 C/A 623-121-7 798-170-9 0.68 1.24 (0.95-1.61) 0.12
CYP19A1 rs2445761 A/G 275-352-130 353-456-148 0.34 1.00 (0.82-1.23) 0.98
CYP19A1 rs2446405 T/A 527-218-21 672-279-29 0.79 1.11 (0.90-1.38) 0.33
BBS4 rs7178130 A/G 280-366-110 388-454-129 0.59 0.88 (0.72-1.08) 0.21
NCP1 rs891286 C/A 145-364-203 194-471-304 0.43 1.09 (0.84-1.40) 0.52

A ancestral allele, D derived allele; N number; HWE Hardy Weinberg equilibrium, OR odds ratio; CI confidence interval; a adjusted for age and sex; bold numbers indicate statistical significance at 5% level.

Huhn et al.

Huhn et al. BMC Medical Genetics 2012 13:94   doi:10.1186/1471-2350-13-94

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