Table 2

Mean difference in fasting glucose and HbA1c levels per weighted allele of genetic risk score in children
Genetic risk score N Fasting glucose (mmol/l) p-value N Adjusted by PCs p-value
FGGRS 573 0.02 (0.01, 0.03) 7.1x10-5 522 0.02 (0.01, 0.03) 0.001
T2DGRS 511 0.003 (−0.01, 0.01) 0.59 467 0.003 (−0.01, 0.01) 0.61
N HbA1c (%) p-value N Adjusted by PCs p-value
FGGRS 1037 0.02 (0.01, 0.02) 1.6x10-6 933 0.02 (0.01, 0.02) 1.4x10-5
T2DGRS 918 0.004 (−0.002, 0.01) 0.20 831 0.005 (−0.002, 0.01) 0.19

FGGRS = fasting glucose genetic risk score.

T2DGRS = type 2 diabetes genetic risk score.

PCs = population stratification principal components.

Bonilla et al.

Bonilla et al. BMC Medical Genetics 2012 13:90   doi:10.1186/1471-2350-13-90

Open Data