Open Access Research article

PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection

Karolina Rembeck1, Cristina Maglio2, Martin Lagging1, Peer Brehm Christensen3, Martti Färkkilä4, Nina Langeland5, Mads Rauning Buhl6, Court Pedersen3, Kristine Mørch5, Gunnar Norkrans1, Kristoffer Hellstrand1, Magnus Lindh1, Carlo Pirazzi2, Maria Antonella Burza2, Stefano Romeo2*, Johan Westin1* and for the NORDynamIC group

Author Affiliations

1 Department of Infectious Diseases/Virology, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden

2 Department of Molecular and Clinical Medicine and Center for Cardiovascular and Metabolic Research, the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

3 Department of Infectious Diseases, University of Southern Denmark, Odense, Denmark

4 Department of Gastroenterology, Helsinki University, Helsinki, Finland

5 Department of Medicine, Haukeland University Hospital and Institute of Medicine, University of Bergen, Bergen, Norway

6 Department of Infectious Diseases, Aarhus University, Aarhus, Denmark

For all author emails, please log on.

BMC Medical Genetics 2012, 13:82  doi:10.1186/1471-2350-13-82

Published: 14 September 2012

Additional files

Additional file 1:

Table S1. Genotype and allele frequencies of the PNPLA3 I148M sequence variant in HCV genotype 2 and 3 individuals.

Format: DOCX Size: 15KB Download file

Open Data