Random-effect OR estimates with the corresponding 95% CIs for the allele contrast of MTHFR C677T and A1298C polymorphisms and the risk of ALL. (A) C677T polymorphism and ALL; (B) A1298C polymorphism and ALL. Studies are displayed by ascending order of publication year. The size of the square represents the weight of the corresponding study. C, Chinese; M, Malays; N, non-Caucasians, admixture of Amerindians, Europeans and Africans; W, mainly Brazilians of Caucasian descent.
Wang et al. BMC Medical Genetics 2012 13:77 doi:10.1186/1471-2350-13-77