Table 4

Regression analysis of eGFR with interaction between homocysteine andMTHFR C677Tgenotype
Males Females
β SE P β SE P
CT −3.54 3.12 0.26 −0.83 2.30 0.72
TT −9.39 3.16 0.003 −0.79 2.48 0.75
log(Hcy) −6.73 1.15 5.7x10-9 −7.10 0.89 1.4x10-15
CT:log(Hcy) 1.52 1.32 0.25 0.42 1.04 0.69
TT:log(Hcy) 3.91 1.29 0.0024 1.04 1.08 0.34

Regression was done with adjustment for age, BMI, systolic and diastolic blood pressures (coefficients not shown). Log(Hcy) was the natural log of plasma homocysteine in μmol/L. β regression coefficient, SE standard error, eGFR was in unit of ml/min/1.73 m2.

Dong et al.

Dong et al. BMC Medical Genetics 2012 13:74   doi:10.1186/1471-2350-13-74

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