Research article
Toll-like receptor gene polymorphisms are associated with allergic rhinitis: a case control study
1 Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden
2 Biomedicine, Kristianstad University, Kristianstad, Sweden
3 Department of Biological Sciences, National University of Singapore, Science Drive 4, Singapore, Singapore, 117543
4 Department of Laboratory medicine, Lund University, Skåne University Hospital, Malmö, Sweden
5 Department of Otolaryngology, National University of Singapore, 10 Lower Kent Ridge Road, Singapore, Singapore, 119260
6 Department of Cell and Organism Biology, Lund University, Lund, Sweden
BMC Medical Genetics 2012, 13:66 doi:10.1186/1471-2350-13-66
Published: 2 August 2012Additional files
Additional file 1:
Investigated genes and number of attempted and genotyped SNPs.
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Additional file 2:
Description of genotyped SNPs.
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Additional file 3:
Description of genotyping and association testing in the two populations.
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Additional file 4:
Complete first experiment association test results in the Swedish population.
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Additional file 5:
Allele and genotype frequencies for all significant SNPs in the Swedish population.
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Additional file 6:
Linkage disequilibrium plot of TLR7-TLR8 gene region constructed using Haploview software and HapMap data (release 24) of the A) CEU population and B) CHB population. The intensity of shading represents D´. S SNPs showing single-point association in the Swedish population. C SNPs showing single-point association in the Chinese population. D SNPs showing single-point association in Møller-Larsen et al. (2008).
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Additional file 7:
Allele frequencies in Chinese males for all significant SNPs
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