Table 1

Minor allele frequency of SNPs from the JAK2 locus in PV

No.

SNP

Minor alleles in PV (n = 28)

Minor alleles in control (n = 28)

P value* (Chi square test)

Odds ratio (95% CI)


No

Yes (homo/hetero)

%

No

Yes (homo/hetero)

%


1

rs10974944 (c→g)

7

21 (15/6)

75

17

11 (3/8)

39.2

0.0069

4.64 (1.49-14.55)

12

rs12686652 (c→g)

6

22 (21/1)

78.6

14

14 (5/9)

50

0.0257

3.67 (1.14-11.79)

13

rs12335546(c→t)

6

22 (21/1)

78.6

19

9 (1/8)

32.1

0.0005

7.74 (2.33-25.75)

19

rs4495487 (t→c)

7

21 (21/0)

75

23

5 (3/2)

17.8

< 0.0001

13.8 (3.79-50.21)

22

rs1028730 (g→a)

6

22 (21/1)

78.5

19

9 (2/7)

32.1

0.0005

7.74 (2.33-25.75)

24

rs12343867(t→c)

7

21 (21/0)

75

17

11 (4/9)

39.3

0.0069

4.64 (1.48-14.55)


* P values were calculated by the cases having minor alleles (homozygous and heterozygous) and cases without minor alleles.

Ohyashiki et al. BMC Medical Genetics 2012 13:6   doi:10.1186/1471-2350-13-6

Open Data