A Structural characteristics of the humanIGF2/ H19 locus with nine exons and five exons for IGF2 and H19 genes respectively. Transcription start site and promoters used are indicated by arrows. Regions of differentially methylated regions (DMRs) are shown with black bars. For each DMR, the number of CpGs analysed is indicated and their relative positions are represented by filled stars corresponding to the methylation site horizontal axis of Figure 1B. B Graph of methylation patterns of the IGF2/H19 locus (expressed as percentage for each CpG) for each case and mean with 95% confidence interval for the 95 control samples.
Murphy et al. BMC Medical Genetics 2012 13:42 doi:10.1186/1471-2350-13-42