Additional file 1.

Figure S1. Linkage disequilibrium (LD) pattern of the proximal region of the obesity associated SNP rs2241423 (marked in red). R-squared scores are used to visualize the LD pattern. Linkage disequilibrium-analysis using confidence intervals according to Gabriel et al. [28] identifies rs2241423 to lie in a haplotype block of about 40 kb encompassing the last intron and exon of MAP2K5 as well as a 10 kb downstream region.

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Rask-Andersen et al. BMC Medical Genetics 2012 13:36   doi:10.1186/1471-2350-13-36