Open Access Research article

Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer

Jesus Lascorz1, Melanie Bevier1, Witigo V Schönfels2, Holger Kalthoff3, Heiko Aselmann2, Jan Beckmann2, Jan Egberts2, Stephan Buch4,5, Thomas Becker2, Stefan Schreiber5, Jochen Hampe5, Kari Hemminki1,6, Asta Försti1,6* and Clemens Schafmayer2,4

1 Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, Heidelberg, 69120, Germany

2 Department of General and Thoracic Surgery, Christian-Albrechts-University, Kiel, Germany

3 Division of Molecular Oncology, Institute for Experimental Cancer Research, Christian-Albrechts-University, Kiel, Germany

4 POPGEN Biobank Project, Christian-Albrechts-University, Kiel, Germany

5 Department of General Internal Medicine, Christian-Albrechts-University, Kiel, Germany

6 Center for Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden

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BMC Medical Genetics 2012, 13:31 doi:10.1186/1471-2350-13-31

Published: 30 April 2012

Additional files

Additional file 1:

Table S1. SNPs in the regions of interest (5′- and 3′-UTR, promoter region and non-synonymous coding SNPs) with MAF > 0 in European population. Table S2. Association of the 16 investigated polymorphisms with survival.

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