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Microdeletion del(22)(q12.2) encompassing the facial development-associated gene, MN1 (meningioma 1) in a child with Pierre-Robin sequence (including cleft palate) and neurofibromatosis 2 (NF2): a case report and review of the literature

Tom B Davidson, Pedro A Sanchez-Lara*, Linda M Randolph, Mark D Krieger, Shi-Qi Wu, Ashok Panigrahy, Hiroyuki Shimada and Anat Erdreich-Epstein*

BMC Medical Genetics 2012, 13:19  doi:10.1186/1471-2350-13-19

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Note while in press

Anat Erdreich-Epstein   (2012-04-25 14:40)  Children's Hospital Los Angeles and University of Southern California

While this manuscript was in press, a paper was published by Reiter et al (Eur J Oral Sci. 2012, 120(2):97-103. doi: 10.1111) in which they found that patients with submucous cleft palate had ��increased allele frequency at SNP rs5752638 of the gene MN1 compared to control individuals. This further supports a possible role for MN1 in cleft palate biology.

Competing interests



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