Table 1

Selected SNPs associated with lung cancer*
First author, year (reference) SNP Gene Chromosomal location Genotyping rate Risk allele Reported OR (95% CI) ‡
McKay, 2008 [4] rs2736100 TERT 5p15 99.5% C 1.18 (1.10-1.26)
McKay, 2008 [4] rs402710† CLPTM1L 5p15 99.6% C 1.22 (1.13-1.32)
McKay, 2008 [4] rs1051730 CHRNA 5, CHRNA 3 15q25 98.8% T 1.35 (1.5-1.45)
You, 2009 [24] rs4083914 RGS17 6q23-25 99.7% G 1.80 (1.36-2.39)
Miki, 2010 [23] rs4488809 TP63 3q28 100% T 1.27 (1.14-1.41)

*Characteristics of the loci from the cited genome-wide association and fine-mapping studies. CI, confidence interval; OR, odds ratio.

†Rs402710 showed relatively litter LD with rs2736100 (D’ = 0.020).

‡ Odds ratio per copy of the risk allele, as reported in the cited study.

Li et al.

Li et al. BMC Medical Genetics 2012 13:118   doi:10.1186/1471-2350-13-118

Open Data