Table 1

Allelic and genotypic frequencies of -1082G > A and -592C > A IL-10 gene promoter variants

Males

Females


Control

(n = 201)

Schizophrenia

(n = 153)

OR (95%CI)

P

Control

(n = 234)

Schizophrenia

(n = 88)

OR (95% CI)

P


Age (years)

37 ± 18

45 ± 13

0.000*

39 ± 18

46 ± 13

0.002*


-1082G > A

Allelic frequencies

n

%

n

%

p

n

%

n

%

G

164

40.8%

111

36.3%

1.21 (0.88-1.66)

0.252

198

42.3%

57

32.4%

1.53 (1.04-2.25)

0.027*

A

238

59.2%

195

63.7%

270

57.7%

119

67.6%

Genotypic frequencies

G/G

38

18.9%

23

15.0%

0.502

33

14.1%

11

12.5%

0.008*

G/A

88

43.8%

65

42.5%

132

56.4%

35

39.8%

A/A

75

37.3%

65

42.5%

69

29.5%

42

47.7%


-592 C > A

Allelic frequencies

n

%

n

%

OR (95%CI)

p

n

%

n

%

OR (95% CI)

p

C

274

75.7%

227

72.8%

1.11 (0.77-1.60)

0.618

298

74.5%

123

69.1%

0.76 (0.51-1.15)

0.213

A

88

24.3%

79

25.3%

102

25.5%

53

29.8%

Genotypic frequencies

C/C

110

60.8%

84

53.8%

0.134

106

53.0%

47

52.8%

0.004*

C/A

54

29.8%

59

37.8%

86

43.0%

29

32.6%

A/A

17

9.4%

10

6.4%

8

4.0%

12

13.5%


Almoguera et al. BMC Medical Genetics 2011 12:81   doi:10.1186/1471-2350-12-81

Open Data