Distribution of risk allele frequency (RAF) in HGDP populations. A. Differences in RAFs between any 2 of the 52 populations in the HGDP panel for the 158 SNPs associated with cardiovascular-diseases traits. B. Differences of RAF () for the comparison of a given tested region (eg, Africa) versus the rest of the world. Negative ΔF indicates that the risk allele has a higher frequency within the tested population than in the rest of the world (see methods section for the denotation of and ).
Ding and Kullo BMC Medical Genetics 2011 12:55 doi:10.1186/1471-2350-12-55