Table 4

Epistatic models: odds ratios (OR) and 95% confidence intervals (95% CI) for all main effects of SNPs.

Additive effects

Dominance effects


aModel 1

Model 2

Model 3

Model 1

Model 2

Model 3


rs9939609

3.515*

(1.41-8.708)

3.281*

(1.32-8.16)

3.719*

(1.43-9.68)

0.515*

(0.31-0.84)

0.531*

(0.32-0.87)

0.506*

(0.30-0.88)


rs1477196

31.589**

(10.27-97.11)

27.551**

(8.98-84.52)

30.111**

(9.65-94.80)

0.509*

(0.31-0.83)

0.515*

(0.32-0.84)

0.458*

(0.27-0.77)


rs7206790

1.865*

(1.11-3.13)

1.802*

(1.07-3.03)

1.888*

(1.08-3.29)

1.074

(0.71-1.63)

1.094

(0.72-1.66)

1.088

(0.68-1.65)


rs8047395

0.247*

(0.10-0.61)

0.262*

(0.11-0.64)

0.281*

(0.12-0.68)

0.822

(0.52-1.30)

0.841

(0.53-1.33)

0.847

(0.52-1.38)


*p-value < 0.05, **p-value < 0.001

aModel 1: without covariate; Model 2: adjust for race and age; Model 3: adjust for race, age and BMI

Kaklamani et al. BMC Medical Genetics 2011 12:52   doi:10.1186/1471-2350-12-52

Open Data