Table 8

Significant fetal pathways in spontaneous preterm delivery

Case-parent triad

Hybrid

KEGG pathway

Pathway Annotation

Single locus

Haplotype

Single locus

Haplotype


hsa04510

Focal Adhesion

0.017

0.019

0.103

0.016

hsa04115

p53 signaling pathway

0.022

0.010

0.054

0.087

hsa01430

Cell Communication

0.024

0.020

0.107

0.012

hsa04512

ECM-receptor interaction

0.024

0.020

0.107

0.012

hsa00361

Gamma-Hexachlorocyclohexane

0.059

0.143

0.016

0.030

hsa00363

Bisphenol A degradation

0.059

0.143

0.016

0.030

hsa04330

Notch signaling pathway

0.061

0.042

0.098

0.112

hsa04210

Apoptosis

0.114

0.211

0.027

0.127

hsa00680

Methane metabolism

0.194

0.261

0.022

0.022

hsa04640

Hematopoietic cell lineage

0.438

0.317

0.083

0.040

hsa04060

Cytokine-cytokine receptor interaction

0.500

0.210

0.080

0.033

hsa04630

Jak-STAT signaling pathway

0.522

0.197

0.043

0.013


Myking et al. BMC Medical Genetics 2011 12:174   doi:10.1186/1471-2350-12-174

Open Data