Open Access Research article

"Single nucleotide polymorphisms of the OPG/RANKL system genes in primary hyperparathyroidism and their relationship with bone mineral density"

María Piedra1, María T García-Unzueta2, Ana Berja1, Blanca Paule1, Bernardo A Lavín2, Carmen Valero3, José A Riancho3 and José A Amado1*

Author Affiliations

1 Endocrinology Service, University Hospital "Marqués de Valdecilla" University of Cantabria-IFIMAV. Avda. de Valdecilla, Santander 39008. SPAIN

2 Clinical Biochemistry Service, University Hospital "Marqués de Valdecilla" University of Cantabria-IFIMAV. Avda. de Valdecilla, Santander 39008. SPAIN

3 Internal Medicine Service, University Hospital "Marqués de Valdecilla". University of Cantabria-IFIMAV. Avda. de Valdecilla, Santander 39008. SPAIN

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BMC Medical Genetics 2011, 12:168  doi:10.1186/1471-2350-12-168

Published: 20 December 2011

Additional files

Additional file 1:

"Distribution Of Fractures And Lithiasis Frequency Among the Genotypes of the Snps Studied In Phpt Patients". This file contains two tables showing the distribution of fractures and lithiasis frequency among the genotype groups of the OPG 163 A/G rs3102735, OPG 245 T/G rs3134070, OPG 1181 G/C rs2073618 and RANKL rs2277438 in PHPT patients.

Format: DOC Size: 47KB Download file

This file can be viewed with: Microsoft Word Viewer

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Additional file 2:

"Comparison Of Biochemical Parameters Among The Genotype Groups of the Snps Studied In Phpt Subjects". This file contains several tables showing the comparison of biochemical parameters among the genotype groups of the OPG 163 A/G rs3102735, OPG 245 T/G rs3134070, OPG 1181 G/C rs2073618 and RANKL rs2277438 in PHPT patients.

Format: DOC Size: 126KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data

Additional file 3:

"Bone Mineral Density Distribution Among The Genotypes of the Snps Studied In Control Subjects". This file contains a table showing the distribution of BMD levels among the three genotype groups of the OPG 163 A/G rs3102735, OPG 245 T/G rs3134070, OPG 1181 G/C rs2073618 and RANKL rs2277438 in the control subjects.

Format: DOCX Size: 14KB Download file

Open Data