Table 1

CNV abnormalities of likely significance in cases with both schizophrenia and epilepsy.

NIMH ID

Sex

Chr.

Start

Size (bp)

CNV

Genes

Validation

DGV


35-70486-01

M

1q21.1

145009580

2814627

Loss

36

Cat

Identical

147-2042-001

M

1q21.1

146506369

1317838

Loss

15

Cat

Identical

143-2166-001

M

1q21.1

145388414

444581

Loss

17

Cat

Identical

147-2403-001

F

2p16.3

50579352

428671

Loss

NRXN1

Cat

Identical

143-2074-001

M

7q11.23

72876647

563297

Gain

15

Cus4

Identical

32-11055

F

15q11-q13

21213950

4994696

Gain

30 genes, SNORDs

Cat

Identical

144-1023-001

M

15q11-q13

22842145

6189545

Gain

28 genes, SNORDs

Cat

Identical

142-1340-001

M

15q13.3

30587903

2320279

Loss

16

MLPA

Identical

145-1243-001

M

16p13.11

15131782

1117825

Loss

10

Cat

Identical

145-1122-001

M

22q11.21

18894894

2569166

Loss

58

Cat

Identical

143-2379-001

M

22q11.21

18894894

2569166

Loss

58

Cat

Identical

143-2623-001

M

22q11.21

18890615

1469118

Loss

36

SNP

Identical


Abbreviations: M, male; F, female; Chr, chromosome; bp, base pair; CNV, copy number variant; DGV, Database of genomic variants. For validation: Cat = 4 × 180 Agilent catalog array; Cus1, Cus2, etc. refer to custom designed focused arrays 1, 2, etc.; MLPA-multiplex ligation-dependent probe amplification, SNP-Illumina 610 quad SNP catalog array.

Stewart et al. BMC Medical Genetics 2011 12:154   doi:10.1186/1471-2350-12-154

Open Data