Table 3

Significantly associated haplotypes in PEPD and CD22 genes

Gene and SNPs in the haplotype

Alleles

Haplotype

Haplotype


Frequency in cases

Frequency in controls

OR [95% CI]

P-value


PEPD

[CTTCA]

0.328

0.367

Reference

rs10500265

C/G

[CTCCA]

0.136

0.154

1.049 [0.761, 1.445]

rs6510383

C/T

[CTTCG]

0.066

0.068

1.062 [0.687, 1.644]

rs7248389

C/T

[CCCCA]

0.115

0.096

1.422 [0.997, 2.028]

0.0026

rs7250833

C/T

[CTCCG]

0.021

0.013

1.872 [0.745, 4.706]

rs2241380

A/G

[GCCTG]

0.095

0.075

1.512 [1.020, 2.242]

[CTCTG]

0.226

0.188

1.435 [1.087, 1.894]

CD22

rs756796

A/G

[GA]

0.105

0.147

0.716 [0.528,0.971]

rs2267574

A/T

[GT]

0.615

0.623

Reference

0.0065

[AT]

0.280

0.230

1.253 [0.995, 1.577]


The most common haplotype was used as a reference (OR of 1) and the other haplotypes were compared to that.

Lillvis et al. BMC Medical Genetics 2011 12:14   doi:10.1186/1471-2350-12-14

Open Data