Open Access Highly Accessed Research article

CYP2C19 and ABCB1 gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population

Paulo CJL Santos1, Renata AG Soares1, Diogo BG Santos1, Raimundo M Nascimento2, George LLM Coelho2, José C Nicolau3, José G Mill4, José E Krieger1 and Alexandre C Pereira1*

Author Affiliations

1 Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of Sao Paulo Medical School, SP, Brazil

2 Departament of Medicine, Ouro Preto Federal University, MG, Brazil

3 Acute Coronary Care Unit, Heart Institute (InCor), University of Sao Paulo Medical School, SP, Brazil

4 Department of Physiology, Espirito Santo Federal University, ES, Brazil

For all author emails, please log on.

BMC Medical Genetics 2011, 12:13  doi:10.1186/1471-2350-12-13

Published: 19 January 2011

Additional files

Additional file 1:

Table S1. Classification of predict metabolic phenotype according to genotype combinations for the CYP2C19*2 and CYP2C19*17 polymorphisms. Classification in EM, IM, PM, UM. Table S2. Distribution of genotype combinations for the CYP2C19*2 and CYP2C19*17 polymorphisms according to ethnic groups. CYP2C19*2 genotypes versus CYP2C19*17 genotypes. Figure S1. Map of Brazil according geographic regions. Studied cities. Figure S2. Map of Brazil according geographic regions showing distribution of variant allele frequencies. Distribution of CYP2C19*2, CYP2C19*17 and ABCB1 polymorphisms.

Format: DOC Size: 492KB Download file

This file can be viewed with: Microsoft Word Viewer

Open Data