Table 3

Characteristics of patients by MTHFD1L genotype (N = 3095).

Outcome

GG

(n = 1366)

AG

(n = 1327)

AA

(n = 402)

P Value

Patient Died

395 (12.8%)

137 (10.0%)

182 (13.7%)

76 (18.9%)

< 0.001

Time (Year)

0.120

Mean ± SD

2.8 ± 1.2

2.8 ± 1.1

2.7 ± 1.2

2.8 ± 1.4

Median (IQR*)

2.7 (2.0, 3.6)

2.8 (2.1, 3.7)

2.6 (2.0, 3.6)

2.8 (1.8, 3.6)

Demographics and History

Age

59.3 ± 12.5

59.9 ± 12.2

59.1 ± 12.8

57.9 ± 12.4

0.010

Sex

0.003

Male

2095 (67.7%)

944 (69.1%)

909 (68.5%)

242 (60.2%)

Female

1000 (32.3%)

422 (30.9%)

418 (31.5%)

160 (39.8%)

Race Category

< 0.001

White/Caucasian

2315 (74.9%)

1189 (87.3%)

943 (71.1%)

183 (45.6%)

Black/African American

607 (19.7%)

109 (8.0%)

303 (22.9%)

195 (48.6%)

Other

167 (5.4%)

64 (4.7%)

80 (6.0%)

23 (5.7%)

Unknown

6

4

1

1

*IQR: interquartile range

Morgan et al. BMC Medical Genetics 2011 12:127   doi:10.1186/1471-2350-12-127