Table 4

Combined genotypic frequencies of GRIA1 (CT) and GRIA3 (TC)

CONTROLS N = 260

CASES N = 244

P-VALUE

OR

95% CI

TWO RISK ALLELES

6+3+31+9 (19%)

24+6+29+22 (33%)

0.00001

3.35

1.96-5.74

ONE RISK ALLELE (GRIA1)

26+74 (39%)

20+63 (34%)

0.03

1.68

1.02-2.77

ONE RISK ALLELE (GRIA3)

26+14 (15%)

27+18 (19%)

0.005

2.28

1.27-4.11

NO RISK ALLELE

71 (27%)

35 (14%)

Genotypes for two risk alleles were: TT/TC + TT/CC + CT/TC + CT/CC; one risk allele (GRIA1): TT/TT + CT/TT; one risk allele (GRIA3): CC/TC + CC/CC; no risk allele: CC/TT.

Formicola et al. BMC Medical Genetics 2010 11:103   doi:10.1186/1471-2350-11-103