Table 3

Genotype and allele frequencies of the SPINK5 SNPs in patients and controls

SNPs

Genotype/allele

Controls(%)

Patients (%)

Odds ratio (95% CI)

P

P*


-206 G>A

AA

48 (6.75)

31 (4.63)

1.00

AG

243(34.18)

192 (28.70)

1.22(0.75–2.00)

GG

420(59.07)

446(66.67)

1.64(1.03–2.63)

0.01

0.05

A

339 (23.84)

254(18.98)

1.00

G

1083(76.16)

1084(81.02)

1.34(1.11–1.60)

0.002

0.01

1103A>G

AA

74(18.05)

92(21.80)

1.00

AG

201(49.02)

192(45.50)

0.77(0.53–1.11)

GG

135(32.93)

138(32.70)

0.82(0.56–1.21)

0.365

A

349(42.56)

376(44.55)

1.00

G

471(57.44)

468(55.45)

0.92(0.76–1.12)

0.429

1156G>A

GG

110(26.83)

111(26.30)

1.00

GA

201(49.02)

192(45.50)

0.95(0.68–1.32)

AA

99(24.15)

119(28.20)

1.19(0.82–1.73)

0.392

G

421(51.34)

414(49.05)

1.00

A

399(48.64)

430(50.95)

1.10(0.90–1.33)

0.352

1258G>A

GG

174(42.44)

169(40.05)

1.00

GA

199(48.54)

201(47.63)

1.04(0.78–1.39)

AA

37(9.02)

52(12.32)

1.45(0.90–2.34)

0.295

G

547(66.71)

539(63.86)

1.00

A

273(33.29)

305(36.14)

1.13(0.93–1.39)

0.236

2475G>T

GG

169(40.05)

191(46.59)

1.00

GT

201(47.63)

169(41.22)

0.97(0.74–1.32)

TT

52(12.32)

50(12.20)

1.07(0.69–1.65)

0.932

G

539(63.86)

551(67.20)

1.00

T

305(36.14)

269(32.80)

1.02(0.83–1.25)

0.835


P* indicates adjusting after Bonferroni correction

Liu et al. BMC Medical Genetics 2009 10:59   doi:10.1186/1471-2350-10-59

Open Data