Table 3 |
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|
Genotype and allele frequencies of the SPINK5 SNPs in patients and controls |
||||||
|
SNPs |
Genotype/allele |
Controls(%) |
Patients (%) |
Odds ratio (95% CI) |
P |
P* |
|
|
||||||
|
-206 G>A |
AA |
48 (6.75) |
31 (4.63) |
1.00 |
||
|
AG |
243(34.18) |
192 (28.70) |
1.22(0.75–2.00) |
|||
|
GG |
420(59.07) |
446(66.67) |
1.64(1.03–2.63) |
0.01 |
0.05 |
|
|
A |
339 (23.84) |
254(18.98) |
1.00 |
|||
|
G |
1083(76.16) |
1084(81.02) |
1.34(1.11–1.60) |
0.002 |
0.01 |
|
|
1103A>G |
AA |
74(18.05) |
92(21.80) |
1.00 |
||
|
AG |
201(49.02) |
192(45.50) |
0.77(0.53–1.11) |
|||
|
GG |
135(32.93) |
138(32.70) |
0.82(0.56–1.21) |
0.365 |
||
|
A |
349(42.56) |
376(44.55) |
1.00 |
|||
|
G |
471(57.44) |
468(55.45) |
0.92(0.76–1.12) |
0.429 |
||
|
1156G>A |
GG |
110(26.83) |
111(26.30) |
1.00 |
||
|
GA |
201(49.02) |
192(45.50) |
0.95(0.68–1.32) |
|||
|
AA |
99(24.15) |
119(28.20) |
1.19(0.82–1.73) |
0.392 |
||
|
G |
421(51.34) |
414(49.05) |
1.00 |
|||
|
A |
399(48.64) |
430(50.95) |
1.10(0.90–1.33) |
0.352 |
||
|
1258G>A |
GG |
174(42.44) |
169(40.05) |
1.00 |
||
|
GA |
199(48.54) |
201(47.63) |
1.04(0.78–1.39) |
|||
|
AA |
37(9.02) |
52(12.32) |
1.45(0.90–2.34) |
0.295 |
||
|
G |
547(66.71) |
539(63.86) |
1.00 |
|||
|
A |
273(33.29) |
305(36.14) |
1.13(0.93–1.39) |
0.236 |
||
|
2475G>T |
GG |
169(40.05) |
191(46.59) |
1.00 |
||
|
GT |
201(47.63) |
169(41.22) |
0.97(0.74–1.32) |
|||
|
TT |
52(12.32) |
50(12.20) |
1.07(0.69–1.65) |
0.932 |
||
|
G |
539(63.86) |
551(67.20) |
1.00 |
|||
|
T |
305(36.14) |
269(32.80) |
1.02(0.83–1.25) |
0.835 |
||
|
|
||||||
|
P* indicates adjusting after Bonferroni correction |
||||||
|
Liu et al. BMC Medical Genetics 2009 10:59 doi:10.1186/1471-2350-10-59 |
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