 Research articleA mitotic recombination map proximal to the APC locus on chromosome 5q and assessment of influences on colorectal cancer riskKimberley Howarth1 1Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, OX3 7BN, UK 2London Research Institute, Cancer Research UK, 44, Lincoln's Inn Fields, London, WC2A 3PX, UK 3Polyposis Registry St Mark's and Northwick Park Hospitals, Watford Road, Harrow, HA1 3UJ, UK 4Academic Histopathology, St Mark's and Northwick Park Hospitals, Watford Road, Harrow, HA1 3UJ, UK 5Colorectal Cancer Genetics Group, Institute of Cell and Molecular Sciences, Bart's and the London Medical School, Queen Mary College, University of London, London, UK
BMC Medical Genetics 2009, 10:54doi:10.1186/1471-2350-10-54
Additional filesAdditional file 1: Fine mapping of mitotic recombination breakpoints close to chr5:68–71 Mb in selected colorectal cancer cell lines. The table shows the allele sizes (bp) at a number of polymorphic markers on proximal chromosome 5q in 6 colorectal cancer cell lines. Format: PDF Size: 17KB Download file This file can be viewed with: Adobe Acrobat Reader Additional file 2: Chromosome 5 SNPs used to assess LOH on the custom Illumina Goldengate arrays. SNP IDs and location are shown. Format: PDF Size: 24KB Download file This file can be viewed with: Adobe Acrobat Reader Additional file 3: Chromosome 5 SNPs between 68 Mb and 80 Mb tested for association with colorectal cancer risk. The table shows genotype counts (nominally AA, AB, BB) in cases and controls, followed by allelic odds ratio, and P value under the allelic χ2 test (or Fisher's exact test for low cell counts). Format: PDF Size: 182KB Download file This file can be viewed with: Adobe Acrobat Reader |
|
|
|
 |  | Log on / register Feedback | Support | My details |
on Google Scholar
author email
corresponding author email|
|
| © 1999-2009 BioMed Central Ltd unless otherwise stated. Part of Springer Science+Business Media. |