Figure 8.

Association between IL18RAP haplotypes and CVD risk in the whole MORGAM cohorts according to BMI. Haplotypic ORs [95% confidence interval] by comparison to the reference TAGTTA haplotype were adjusted for cohorts, age and gender, separately for subjects below (diamonds) and above (squares) the population-specific median of BMI. The global test of association was neither significant in the group of individuals below (χ² = 5.379 with 6 df, p = 0.496) nor above (χ² = 11.18 with 6 df, p = 0.083) the median of BMI. Polymorphisms are ordered according to their position on the genomic sequence.