Table 1

Characteristics of FPLD patients compared to controls

GL2784

GL2990

GL0658

GL0096


Diagnosis

Control

Control

FPLD3

FPLD2

Mutation

Wild-type

Wild-type

PPARG F388L

LMNA R482Q

Age (years)

24

50

49

63

Sex

Female

Female

Female

Female

Height (m)

1.63

1.60

1.52

1.53

Weight (kg)

61.7

89.1

80.2

58.1

Body mass index (kg/m2)

23.5

34.8

33.4

24.8

Waist circumference (cm)

78.8

103.6

105.7

88.3

Waist-to-hip circumference ratio

0.88

0.86

0.88

0.92

Blood pressure (mmHg)

113/63

154/89

138/88 (treated)

131/76 (treated)

BIA measures (PBF, %)

total body

28.0 ± 0.2

47.5 ± 0.2

31.8 ± 0.2

29.7 ± 0.1

right leg

31.4 ± 0.1

49.5 ± 0.1

44.0 ± 0.2

36.8 ± 0.1

left leg

31.3 ± 0.1

49.2 ± 0.1

47.9 ± 0.5

37.7 ± 0.1

Mean sc+inf volume/slice (%)

mid-calf

26.3 ± 1.1

34.8 ± 1.5

19.2 ± 1.7

N/A

mid-thigh

44.3 ± 2.1

56.1 ± 1.5

34.4 ± 2.5

24.3 ± 3.7

Overall sc+inf volume (%)

mid-calf

26.2

34.7

19.2

N/A

mid-thigh

44.5

56.1

34.5

24.5


Abbreviations: FPLD, familial partial lipodystrophy; BIA, bioimpedance analysis; PBF, percent body fat; MRI, magnetic resonance imaging; sc+inf fat, subcutaneous plus infiltrated fat; N/A, could not be assessed (no visible subcutaneous fat)

Al-Attar et al. BMC Medical Imaging 2006 6:11   doi:10.1186/1471-2342-6-11

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