Pattern of partial high-signal intensity involving more than 50% of the node on SPIO-enhanced MR imaging. (a) The node showed high-signal intensity before administration of superparamagnetic iron oxide (SPIO). (b) After administration of SPIO, the node showed partial high-signal intensity involving more than 50% and was diagnosed as malignant (arrow). (c) Histological findings showed the presence of macro-metastases within the node (arrowheads).
Motomura et al. BMC Medical Imaging 2013 13:32 doi:10.1186/1471-2342-13-32