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Table 1
Model parameters and estimations
parameter	description	baseline value	references

1/μ_A	mean infectious period of asymptomatic infection	4.1 days	[3,6,7]
1/μ_U	mean infectious period of untreated symptomatic infection	4.1 days	[3,6,7]
1/μ_T	mean infectious period of treated symptomatic infection	4.1 days	[3,6,7]
d_U	death rate of untreated symptomatic infection	0.002 day^-1	[12,19]
d_T	death rate of treated symptomatic infection	0.001 day^-1	[12,19]
d_U,r	death rate of resistant infection (low fitness)	0.0002 day^-1	[12,19]
d_r,U	death rate of resistant infection (high fitness)	0.0008 day^-1	[12,19]
δ _A	relative transmissibility of asymptomatic infection	0.142	[6,7,19]
δ _T	relative transmissibility of treated symptomatic infection	0.4	[3,12,19]
δ _r	relative transmissibility of resistant strain (high fitness)	0.9	[19,27]
p	probability of developing clinical symptoms	0.67	[6,7]
α	rate of emergence of de novo resistance	0.018 day^-1	[19,25]
γ	rate of conversion between resistant mutants	0.0036 day^-1	[19,25]
q	treatment level	variable

Description of the model parameters with their values obtained from the published literature.
Arino et al. BMC Infectious Diseases 2009 9:8 doi:10.1186/1471-2334-9-8

Table 1