Table 1

Risk factors that were significantly associated with CSF pleocytosis in children with HFMD in the first phase of the study (2000 to 2003).

Risk factors

p value

Odds ratio

95% CI


Total duration of fever ≥ 3 days

< 0.0001

6.52

2.83 – 14.99

Peak temperature ≥ 38.5°C

0.0192

2.27

1.14 – 4.51

History of lethargy

0.001

3.18

1.60 – 6.35


Note: The Hosmer-Lemeshow statistics indicated a non-significance of lack of fit (χ2 = 2.163, p = 0.904).

CSF: Cerebrospinal fluid

HFMD: Hand, foot, and mouth disease

Ooi et al. BMC Infectious Diseases 2009 9:3   doi:10.1186/1471-2334-9-3

Open Data