Table 1 |
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|
Baseline patient characteristics |
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|
Colistin (n = 32) |
Tobramycin (n = 32) |
P value |
|
|
|
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|
Number of patients with chronic diseases at the time of admission (%) |
9 (28) |
12 (37.5) |
0.65 |
|
Median duration of treatment (IQR) |
8 (5 to 13) |
7 (6 to 10) |
0.72 |
|
Mean age in years (± SD) |
43.5 (± 15.6) |
45.6 (± 18.2) |
0.69‡ |
|
Mean APACHE score at ICU admission (± SD) |
14.4* (± 5.1) |
14.8** (± 5.4) |
0.77‡ |
|
Dialysis at baseline (%) |
3 (9.4) |
5 (15.6) |
0.60† |
|
Median baseline creatinine (IQR) umol/L |
76 (53 to 128) |
56 (45 to 91) |
0.08 |
|
Site of A. baumannii infection: |
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|
Bloodstream infection |
10 (31%) |
10 (31%) |
1.00▫ |
|
Sputum/tracheal aspirate |
22 (72%) |
28 (88%) |
0.13† |
|
Wound pus swab |
6 (18.8%) |
11 (34.4%) |
0.75▫ |
|
Cerebrospinal fluid |
1 (3.1%) |
0 |
NA |
|
Central venous catheter tip |
10 (31%) |
9 (28%) |
0.44▫ |
|
Urine |
5 (15.6%) |
4 (12.5%) |
1.00† |
|
|
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|
*data available for 25 participants **data available for 21 participants † Fisher's Exact Test ‡ Two sample t- test • Wilcoxon rank sum test ▫ Two sample test of proportion |
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|
Gounden et al. BMC Infectious Diseases 2009 9:26 doi:10.1186/1471-2334-9-26 |
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