Table 1 |
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Baseline characteristics of all patients and according to the maximum procalcitonin levels measured (PCTmax) |
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Characteristics |
All n = 34* |
PCT<0.1 n = 3 |
0.1<PCT<0.25 n = 7 |
PCT>0.25 n = 22 |
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|
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Age, yr |
70 ± 10 |
71 ± 10 |
71 ± 10 |
69 ± 10 |
|
Male sex, no.(%) |
28(82) |
2(66) |
6(86) |
18(82) |
|
SAPS II score |
37 [20-50] |
27 [23-30] |
31 [24-44] |
40 [34-62] |
|
LOD score |
6 [4-10] |
6 [4-10] |
6 [411] |
6 [4-10] |
|
Comorbidities, no (%) |
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|
Current smokers, |
11(32) |
0 |
4(57) |
7(32) |
|
Chronic alcohol abuse |
8(24) |
2(66) |
1(14) |
4(18) |
|
Obesity |
12(35) |
3(100) |
2(29) |
5(23) |
|
Coronary artery disease |
14(41) |
1(33) |
3(43) |
9(41) |
|
Hypertensive heart disease |
17(50) |
1(33) |
2(29) |
12(55) |
|
Congestive heart disease |
9(26) |
1(33) |
0 |
8(36) |
|
Diabetes mellitus |
13(38) |
0 |
3(43) |
8(36) |
|
Chronic pseudomonas colonisation, no (%) |
4(12) |
0 |
2(29) |
2(9) |
|
Antibiotics in 24 H prior ICU admission¶, no (%) |
11(32) |
0 |
2(29) |
8(36) |
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During the previous 30-day period¶¶ |
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|
Antibiotics for AECOPD |
7(20) |
0 |
2(29) |
5(23) |
|
Oral steroid therapy for AECOPD |
8(24) |
1(33) |
3(43) |
5(23) |
|
Severity of COPD, no (%) |
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|
GOLD stage I (mild) |
2(6) |
0 |
0 |
2(9) |
|
GOLD stage II (moderate) |
9(26) |
1(33) |
0 |
6(27) |
|
GOLD stage III (sever) |
3(9) |
0 |
0 |
3(14) |
|
GOLD stage IV (very sever) |
20(59) |
2(66) |
7(100) |
11(50) |
|
Home oxygen, no (%) |
18(53) |
2(66) |
5(71) |
11(50) |
|
Home non-invasive ventilation, no (%) |
6(18) |
1(33) |
2(28) |
3(14) |
|
Oral or inhaled steroid, no (%) |
19(56) |
2(66) |
6(85) |
10(45) |
|
Examination at ICU admission, no (%) |
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|
Dyspnea |
34(100) |
3(100) |
7(100) |
22(100) |
|
Cough |
11(32) |
1(33) |
3(43) |
7(32) |
|
Sputum |
16(47) |
2(66) |
3(43) |
11(50) |
|
Rales |
15(44) |
1(33) |
1(14) |
12(55) |
|
Wheezing |
16(47) |
2(66) |
6(86) |
7(32) |
|
Body temperature, °C |
37.3 ± 1.2 |
37.0 ± 0.7 |
36.5 ± 0.7 |
37.7 ± 1.3 |
|
Leucocytes count (×109/L) |
13.7 ± 6.4 |
11.2 ± 0.4 |
12.5 ± 3.4 |
14.9 ± 7.4 |
|
Pneumonia severity index (PSI) |
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|
PSI I, II, III |
4(11) |
1(33) |
2(28) |
1(5) |
|
PSI IV |
14(42) |
1(33) |
4(57) |
8(36) |
|
PSI V |
16(47) |
1(33) |
1(14) |
13(59) |
|
|
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|
Values are given as No.(%), median [25%-75% interquartile range], or mean ± standard deviation * Levels of procalcitonin (PCT) were assessed in 32/34 patients. PCT is given in μg/L ¶ One patient receiving antibiotic in 24 h prior ICU was not assessed for PCT levels ¶¶ Patients treated with antibiotic or oral steroid during the previous 30-day period for exacerbation of COPD were exclusive of those receiving antibiotic in 24 h prior ICU |
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|
Daubin et al. BMC Infectious Diseases 2009 9:157 doi:10.1186/1471-2334-9-157 |
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