Research article
Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity
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* Corresponding author: Claire F Kubelka claire@ioc.fiocruz.br
1 Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
2 Programa de Computação Científica, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
3 Hospital Universitário Antonio Pedro, Universidade Federal Fluminense, Niterói, Brazil
4 Laboratório de Imunologia Viral, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
5 Laboratório de Flavivirus, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
6 Laboratório de Imunofarmacologia, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil
BMC Infectious Diseases 2008, 8:86 doi:10.1186/1471-2334-8-86
Published: 25 June 2008Additional files
Additional file 1:
Blood collection time in patients during dengue fever. Twenty patients had mild dengue and thirty-nine had severe dengue. Box-and-whiskers graph. The box extends from the 25th to the 75th percentile and the line at the middle is the median. The error bars, or whiskers extend down to the lowest value and up to the highest. Mann-Whitney U test was used to evaluate differences between blood collection time from severe and mild dengue patients and no significant difference was found (P = 0.7851).
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Additional file 2:
Time dependent cytokine levels in plasma from patients with mild and severe dengue. Twenty patients had mild dengue and thirty-nine had severe dengue. Dots represent single patient's cytokine measurements.
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