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Description of the blood stream infection episodes at the time of the first positive blood culture drawing according to the sepsis type (i.e. primary or secondary sepsis). |
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| Mean (SD) or number (%) |
Primary sepsis n = 117 |
Secondary sepsis n = 62 |
p |
|
|
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| Time elapsed from ICU admission (N. of days) |
2.0 (2.4) |
15.6 (16.9) |
< 0.0001 |
|
|
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| SOFA score |
6.9 (4.1) |
7.2 (3.9) |
0.706 |
|
|
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| Platelet count (cell/mm3) |
185,459 (118,375) |
235,935 (183,485) |
0.028 |
|
|
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| Creatininemia (μmol/L) |
198.7 (168.5) |
163.2 (129.2) |
0.149 |
|
|
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| Prothrombin time (%) |
58.8 (21.9) |
62.8 (19.9) |
0.248 |
|
|
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| Septic shock |
60 (51.7) |
31 (50.0) |
0.302 |
|
|
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| Nosocomial sepsis ICU acquired sepsis |
34 (35.8) 31 (26.5) |
62 (100) 52 (83.9) |
< 0.0001 < 0.0001 |
|
|
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| Infection source |
0.002 |
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| Lung |
30 (25.6) |
12 (19.3) |
0.447 |
| Abdominal |
23 (19.7) |
18 (29.0) |
0.217 |
| Soft tissues |
13 (11.1) |
4 (6.4) |
0.456 |
| Urinary tract |
24 (20.5) |
2 (3.2) |
0.004 |
| Miscellaneous |
9 (7.7) |
5 (8.1) |
0.480 |
| Unknown |
18 (15.4) |
21 (33.9) |
0.008 |
|
|
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| Involved pathogen bacteria |
113 (95.6) |
41 (64.4) |
< 0.0001 |
| Gram positive |
51 (43.6) |
20 (32.2) |
|
| Gram negative |
62 (53.0) |
21 (33.9) |
|
| fungi |
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| Candida spp |
4 (3.4) |
21 (33.9) |
|
|
|
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| Previous exposure to antibiotic therapy with in vitro activity against the involved pathogen |
16 (13.7) |
21 (33.9) |
0.003 |
|
|
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| Previous exposure to steroids |
9 (7.7) |
23 (37.1) |
< 0.0001 |
|
|
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| Time elapsed between bacteremia onset and PCT sampling (N. of minutes) |
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| Mean (SD) |
-169.7 (382.6) |
6.3 (455.4) |
0.011 |
| Median [range] |
-13.0 [-1072–720] |
0.0 [-720–720] |
|
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ICU: Intensive Care Unit; SOFA: Sepsis-related Organ Failure Assessment. | |||
Charles et al. BMC Infectious Diseases 2008 8:163 doi:10.1186/1471-2334-8-163 |
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