Research article

Pediatric campylobacteriosis in northern Taiwan from 2003 to 2005

Ji-Rong Yang¹ , Ho-Sheng Wu^1,2 , Chuen-Sheue Chiang^1,3 and Jung-Jung Mu¹

¹Research and Diagnostic Center, Centers for Disease Control, Department of Health, Taipei, Taiwan

²School of Medical Laboratory Science and Biotechnology, Taipei Medical University, Taipei, Taiwan

³Center of General Education, National Taipei College of Nursing, Taipei, Taiwan

author email corresponding author email

BMC Infectious Diseases 2008, 8:151doi:10.1186/1471-2334-8-151

Published:	31 October 2008

Abstract

Background

There has been a marked increase in the incidence of, and concern regarding, human Campylobacter jejuni and C. coli infections worldwide during the last decade. As the highest infectious disease control apparatus in Taiwan, we aimed to describe the character of Campylobacter isolates from infected children, as well as basic information about the patients, from December 2003 to February 2005.

Methods

A total of 894 fecal specimens were collected by several clinics and hospitals from children who had diarrhea, followed by plating onto selective media. Drug susceptibility test of the isolates from these specimens were conducted by disc diffusion method and their serotypes were also studied using commercial antisera made in Japan.

Results

The isolation rate of Campylobacter during these 15 months was 6.8% and was higher in winter (11.1%) than in other seasons. C. jejuni was the most prevalent (95.1%) species in northern Taiwan, comparable to other developed countries. Among the 61 Campylobacter isolates, most were resistant to tetracycline (93.4%), nalidixic acid (91.8%), ciprofloxacin (90.2%), and ampicillin (85.5%). Erythromycin-resistant isolates represented 3.3% of all isolates, suggesting that this drug may be the first choice for treatment. The serotypes of the 61 isolates were demonstrated and only 41.4% were typable.

Conclusion

In this study, the Taiwan CDC provided an epidemiological analysis of Campylobacter infection, including the isolation rate, age, seasonal distribution, antimicrobial drug susceptibility patterns, and serotypes of the isolates from pediatric patients in northern Taiwan from 2003 to 2005.