|
Cure rates stratified according to infestation intensity (assessed by 3 minutes of visual inspection before treatment) |
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| Dimeticone group |
Permethrin group |
P value |
Effect size |
|||
| Cured/total |
% (95% CI) |
Cured/total |
% (95% CI) |
RR (95% CI) |
||
|
|
||||||
| Low or moderate infestationa |
||||||
| Day 2 |
37/38 |
97.4% (86.2% – 99.9%) |
23/31 |
74.2% (55.4% – 88,1%) |
P = 0.004 |
1.31 (1.06–1.63) |
| Day 7 |
32/38 |
84.2% (68.7% – 94.0%) |
23/31 |
74.2% (55.4% – 88,1%) |
P = 0.3 |
1.14 (0.88–1.46) |
| Day 9 |
36/37 |
97.3% (85.5% – 99.9%) |
25/31 |
80.6% (62.5% – 92.5%) |
P = 0.02 |
1.21 (1.01–1.45) |
| Heavy infestationb |
||||||
| Day 2 |
32/35 |
91.4% (76.9% – 98.2%) |
25/41 |
61.0% (44.5% – 75.8%) |
P = 0.002 |
1.50 (1.15–1.95) |
| Day 7 |
15/35 |
42.9% (26.3% – 60.4%) |
20/41 |
48.8% (32.9% – 64.9%) |
P = 0.6 |
0.88 (0.54–1.44) |
| Day 9 |
34/35 |
97.1% (85.1% – 99.9%) |
23/40 |
57,5% (40.9% – 73.0%) |
P < 0.0001 |
1.69 (1.29–2.22) |
|
a < 5 active head lice at the beginning of the study; see material and methods b ≥ 5 active head lice | ||||||
Heukelbach et al. BMC Infectious Diseases 2008 8:115 doi:10.1186/1471-2334-8-115 |
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