Table 2

Evaluation of blood stream infections.

Item
Group 1
(heparin)
Group 2
(TauroLock™)
P value

No. of BSI events
30
25

No. (%) of patients with at least 1 BSI
24 (27)
21 (24)
0.74
No. (%) of BSI with CoNS* or MRSE§
14 (47)
3 (11)
0.004

     CoNS: 4 (13)
     CoNS: 3 (11)


     MRSE: 10 (33)
     MRSE: 0 (0)

Incidence densityfor All BSI events (CI95)
4.93 (3.33–7.04)
3.82 (2.52–5.56)
0.35
Incidence densitycalculated with the number of specific isolates



     BSI with CoNS/MRSE
2.30 (1.26–3.86)
0.45 (0.09–1.31)
0.004
     BSI other Gram positive
0.66 (0.18–1.68)
1.19 (0.52–2.35)
0.32
     BSI E. coli
0.66 (0.18–1.68)
1.49 (0.72–2.74)
0.15
     BSI all Gram negative
1,97 (1.02–3.44)
2.24 (1.25–3.69)
0.74

Group 1 = heparin (2004–2005) vs. group 2 = TauroLock™ (2005–2006)

* CoNS = coagulase-negative Staphylococci (methicillin-sensitive)

§MRSE = methicillin-resistant coagulase-negative Staphylococci

+ The percentage refers to all documented BSI in this group (100%).

‡ The ID refers to the number of events per 1000 inpatient CVAD utilization days.

Δ IQR = interquartile range, 25–75. Percentile

Simon et al. BMC Infectious Diseases 2008 8:102   doi:10.1186/1471-2334-8-102