Table 1

Antiviral treatment schedule and effects

Parameter

Value

Source

Average time for seeking medical help after symptom onset

D_D = 24 h

assumed

therapeutic window (after onset of symptoms)

D_T = 48 h

Fachinformation Roche

fraction eligible to receive treatment

assumed

• severe cases who can stay at home

f_V = 100%

• extremely severe cases who need hospitalization

f_X = 100%

treatment reduces the duration of the infectious period

f_D = 25%

Fachinformation Roche

treatment reduces infectiousness by

f_I = 80%

Longini (2004)

treatment reduces hospitalizations by

f_H = 50%

Kaiser (2003)

Duerr et al. BMC Infectious Diseases 2007 7:76   doi:10.1186/1471-2334-7-76