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Logistic regression analysis of risk factors for intra-hospital death from laboratory-confirmed bloodstream infection and clinically suspected systemic infection |
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| Characteristic |
Laboratory-confirmed bloodstream infection |
Clinically suspected systemic infection |
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|
|
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| HIV-status analyzed |
No |
Yes |
No |
Yes |
|
|
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| No. of observations |
n = 216 |
n = 128 |
n = 1527 |
n = 790 |
|
|
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| OR (95%CI) |
OR (95%CI) |
OR (95%CI) |
OR (95%CI) |
|
| Male sex |
* |
* |
0.8 (0.60–1.05) |
* |
| Neonate (≤ 1 month) |
* |
* |
* |
0.7 (0.45–1.15) |
| Malnutrition |
1.9 (0.95–3.88) |
* |
2.1 (1.47–2.90)‡ |
1.6 (0.96–2.55) |
| HIV infection |
NA |
3.4 (1.22–9.40)† |
NA |
2.1 (1.29–3.26)† |
| Other underlying infectious disease |
* |
* |
1.8 (1.13–2.87)† |
* |
| Underlying non-infectious disease |
* |
* |
* |
* |
| Malaria |
* |
* |
* |
* |
| Hospital-acquired infection |
* |
* |
* |
* |
| Polymicrobial infection |
* |
* |
* |
* |
| Growth in blood-culture of: |
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| - Enterobacteriaceae |
3.5 (1.71–7.03)† |
5.6 (2.06–14.95)† |
3.3 (2.09–5.34)‡ |
4.2 (2.27–7.65)‡ |
| - Non -Enterobacteriaceae |
2.4 (0.92–6.13) |
4.0 (0.99–16.45) |
2.4 (1.02–5.46)† |
2.7 (0.80–8.81) |
| - Candida spp. |
2.6 (0.91–7.29) |
2.9 (0.70–12.09) |
2.5 (1.02–6.03)† |
* |
| Inappropriate antimicrobial treatment |
2.1 (1.09–4.16)† |
2.3 (0.95–5.58) |
2.1 (1.14–3.93)† |
1.7 (0.76–3.73) |
|
OR, odds ratio; 95%CI, 95% confidence interval. *Variables with P > 0.2 were removed from the models. Statistically significant risk factors are marked † P < 0.05 and ‡ P < 0.001. | ||||
Blomberg et al. BMC Infectious Diseases 2007 7:43 doi:10.1186/1471-2334-7-43 |
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